Some refractive procedures carry higher retinal risks, study finds
Certain refractive procedures for myopia pose a greater risk of postoperative retinal problems than other refractive procedures, a large cohort study suggests. Phakic IOLs created the highest risk for retinal detachment in the study, followed by LASIK and then photorefractive keratectomy.
José Ma. Ruiz-Moreno, MD, and colleagues at the Miguel Hernández University School of Medicine evaluated 9,239 eyes of 5,099 patients who underwent refractive procedures for the correction of myopia and who had a minimum of 12 months follow-up. Stable myopia, a normal anterior segment with an anterior chamber depth greater than 3.4 mm, endothelial cell density greater than 2250 cell/mm2, and corneal thickness sufficient to remain greater than 370 µm postoperatively were among the inclusion criteria. Patients were excluded if they had previous corneal disease, glaucoma or a history of ocular trauma.
Photorefractive keratectomy (PRK) was performed on 5,936 eyes with a mean spherical equivalent of 4.71 D. LASIK was performed on 3,009 eyes with a mean spherical equivalent of 13.5 D. Anterior chamber phakic IOL implantation was performed in 294 eyes with a mean spherical equivalent refraction of 18.5 D. Follow-up was at 1, 3, 6 and 12 months and once yearly thereafter.
Retinal detachment occurred at a mean of 53.6 months after PRK in nine eyes (0.15%), 24.6 months after LASIK in 11 eyes (0.36%) and 20.5 months after phakic IOL implantation in 12 eyes (4%). Choroidal neovascularization occurred in 10 eyes that had undergone LASIK (0.33%), in seven with a phakic IOL (2.38%) and in one that underwent PRK (0.01%).
The study is published in the September/October issue of Journal of Refractive Surgery.