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SLT more effective as primary treatment than secondary following glaucoma therapy, study finds
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SAN DIEGO — A higher mean IOP decrease and reduction were achieved in glaucoma cases that received selective laser trabeculoplasty without previous medical therapy than those that did, a study found.
Lawrence F. Jindra, MD, and colleagues presented results of a large retrospective chart review in a poster study at the American Society of Cataract and Refractive Surgery meeting here. The study looked at the impact of previous prostaglandin treatment on SLT in lowering IOP in glaucoma patients.
"Our findings ... suggest that the IOP-lowering effects of SLT treatment are more effective when used as initial therapy than when used as adjunctive therapy following treatment with prostaglandin meds," they said.
The study examined 1,614 of 3,034 eyes in a case series that received SLT over 8 years. There were two groups: 236 eyes that were treated initially with prostaglandins followed by SLT and 1,378 eyes treated only with SLT.
Dr. Jindra and colleagues found a mean IOP decrease of 31% for SLT-only eyes and 23% for prostaglandin-SLT eyes and a 35% greater mean IOP reduction in SLT-only eyes.
- Disclosure: Dr. Jindra has received honoraria from Ellex Corporation in the last year; his co-authors have no financial disclosures.