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SLT may reduce IOP in patients with uncontrolled pseudoexfoliation glaucoma
Ophthalmic Surg Lasers Imaging. 2011;42(5):390-393.
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In patients with uncontrolled pseudoexfoliation glaucoma, selective laser trabeculoplasty reduced IOP by nearly one-third, a study found.
The study included 57 eyes of 57 patients with uncontrolled pseudoexfoliation glaucoma and an IOP exceeding 23 mm Hg who underwent SLT. IOP was measured at 1 hour, 1 day, 1 week, and 1, 3, 6 and 12 months postoperatively.
At 12 months, mean IOP in all patients had decreased by 31.5%, from 26.01 mm Hg to 17.8 mm Hg (P < .001). Within 24 hours postop, 30 eyes (67%) experienced complications such as conjunctival redness and infection. Within 1 hour postop, two eyes (3.5%) experienced an increase in IOP greater than 5 mm Hg, which resolved within 24 hours with topical medication.
No serious adverse effects related to SLT were reported.
"Ours is the first prospective study on SLT treatment in patients with [pseudoexfoliation glaucoma] as a uniform group. ... The hypotensive effect in our study group was stable for 12 months after treatment, with stable visual acuity and visual fields," the study authors said. "Additionally, gonioscopy did not detect any scarring or formation of peripheral anterior synechiae."