June 18, 2004
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Similar nerve damage seen in normal-tension, high-tension glaucomas

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Characteristics of the retinal nerve fiber layer do not vary significantly between patients with high-tension glaucoma and patients with normal-tension glaucoma, according to a study in the journal Optometry and Vision Science.

The study authors said they found similarities in the damage to areas of the retinal nerve fiber layer (RNFL) in both glaucoma groups, suggesting that eyes with both types of glaucoma may undergo similar pathological processes.

Kwok Hei Mok, PhD, FAAO, FVCO, and colleagues conducted the study, which included 38 normal-tension glaucoma (NTG) patients, 48 high-tension glaucoma (HTG) patients and 48 normal patients, all matched for age and refraction.

According to the study authors, RNFL thicknesses in the inferotemporal regions were significantly lower compared to the superotemporal regions in both glaucoma groups (P < .001). Several other optical coherence tomography parameters were also significantly lower among the HTG and NTG patients compared to the normal patients. These included average, superior, inferior, inferotemporal and superotemporal values (P < .01).