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Silicone oil tamponades useful for ‘severely diseased’ eyes with PDR, study finds

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NEWARK, N.J. — Silicone oil tamponade is useful in “severely diseased” eyes with proliferative diabetic retinopathy, say researchers here at the University of Medicine and Dentistry of New Jersey. The results are good, even in the presence of rubeosis iridis and neovascular glaucoma, fibrinoid syndrome or in cases of previously failed vitrectomy, the study authors add.

Marco Zarbin and colleagues retrospectively reviewed the records of 23 eyes of 21 patients with proliferative diabetic retinopathy (PDR) who had undergone par plana vitrectomy with silicone oil infusion. Of the 23 eyes, 48% (11 eyes) had previously failed vitrectomy. Follow-up ranged from 1 to 25 months.

Seventeen of the 23 eyes achieved retinal reattachment with one surgery. The retina was attached in eight of those 11 eyes with a single procedure. Ten eyes experienced an improvement in postoperative VA, three eyes remained unchanged and VA decreased in 10 eyes.

The study is published in the March issue of British Journal of Ophthalmology.