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Sclerectomy with implant has good results in 10-year follow-up of glaucoma treatment

J Glaucoma. 2008:17(8):680-686.

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Deep sclerectomy with collagen implant, a nonpenetrating filtration procedure used in lieu of conventional trabeculectomy, offers satisfactory results after 10 years of follow-up.

In a clinical, prospective, monocentric, nonrandomized, unmasked study, deep sclerectomy with collagen implant was performed on 105 eyes of 105 patients with open-angle glaucoma to evaluate long-term success rate and postoperative complications. This procedure was used to try to avoid postoperative complications of trabeculectomy.

Preoperative IOP was 26.8 ± 7.7 mm Hg; 10 years postop, it was 12.2 ± 4.7 mm Hg, a decrease of 54.5%.

Complication rates appear to be lower for deep sclerectomy with collagen implant than for trabeculectomy; additional procedures, such as injection of 5-fluorouracil for bleb fibrosis and goniopuncture, were more frequently performed in the implant group, the study authors said.