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Scientists find gene for some glaucomas
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FARMINGTON, Conn. — Scientists here believe they have discovered the gene responsible for causing some cases of primary open-angle glaucoma and normal-tension glaucoma.
Labeled the Optineurin gene, it was identified during a study of 54 families with adult-onset primary open-angle glaucoma (POAG) and 124 sporadic POAG patients, the majority of whom are normal-tension glaucoma patients. According to the researchers, Optineurin may be responsible for 16.7% of hereditary forms of normal-tension glaucoma, with an additional risk factor of 13.6% in both familial and sporadic cases.
Robert Ritch, MD, of New York Eye and Ear Infirmary, labeled the discovery a ”major breakthrough” in glaucoma research and diagnosis. A screening test based on the Optineurin gene may help identify normal-tension glaucoma early and allow earlier initiation of treatment, he said.
InSite Vision has licensed exclusive worldwide rights to the gene.