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Room air tamponade achieves equivalent macular hole closure rate with shorter prone positioning

Graefes Arch Clin Exp Ophthalmol. 2009;247(11):1455-1459.

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Room air tamponade used for macular hole closure demonstrated similar closure rates as gas tamponade despite a shorter prone positioning in the postoperative recovery period, according to a study.

In a retrospective analysis of 91 eyes that received tamponade with SF6 gas and 65 eyes that received tamponade with room air, initial closure rates were 90.1% in the gas group vs. 92.3% in the air group. However, duration of prone position period after surgery was significantly longer in the gas group vs. air group: 7.44 days vs. 3.83 days (P < .0001).

Mean preoperative hole diameter was 352 µm in the gas group and 370 µm in the air group. The difference was not statistically significant.

Overall, eyes with a macular hole larger than 300 µm were more prone to surgical failure, according to the study.