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Risk of microbial keratitis greater in daily disposable contact lens users

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A prospective, case-controlled study of contact lens users admitted to an eye hospital in London for microbial keratitis showed a greater risk of developing the infection among users of daily disposable contact lenses compared with planned replacement soft lenses.

John K.G. Dart, DM, FRCOphth and colleagues at Moorfields Eye Hospital found that the risk of developing microbial keratitis differed among types of disposable contacts, and the risk was reduced in users of rigid lenses compared with soft lenses.

There was no difference in risk in wearers of silicone hydrogel lenses.

Although the risk of developing microbial keratitis was greater among daily disposable wearers, the risk of vision loss was lower compared with planned replacement soft contact lens users (P = .05).

In addition, the relative risk of developing microbial keratitis was 5.4 times higher among any type of overnight lens compared with daily replacement lenses (P < .001), according to the study, published in the October issue of Ophthalmology.