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Risk factors identified for retinal degeneration in patients with central serous chorioretinopathy
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Among patients with central serous chorioretinopathy, a disease duration of longer than 5 years and subretinal fibrosis can contribute to the development of posterior cystoid retinal degeneration, a retrospective study found.
Felice Cardillo Piccolino, MD, and colleagues studied possible associative factors for the development of posterior cystoid retinal degeneration among 51 eyes of 51 patients with chronic central serous chorioretinopathy and subretinal or intraretinal exudation.
Twenty-four eyes (47%) had posterior cystoid retinal degeneration, and 27 eyes (53%) had serous macular detachment with no cystoid retinal changes, the authors noted.
Multivariate analysis found that the development of posterior cystoid retinal degeneration was significantly associated with a disease duration exceeding 5 years (P = .004) and subretinal fibrosis (P = .015), according to the study, published in the September issue of Retina.