August 30, 2010
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Retinal vein occlusion associated with higher rate of stroke

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VANCOUVER, British Columbia — Patients with retinal vein occlusions appear to have significantly more comorbidities, as well as an increased risk for cerebrovascular accident.

Nancy M. Holekamp, MD
Nancy M. Holekamp

In a cohort of patients gathered from a health care utilization database, rates of angina, cardiac arrhythmia, diabetes, heart disease, acute thrombolytic events, hyperlipidemia, hypertension and cerebrovascular accident were all significantly higher among 4,500 patients with retinal vein occlusions compared with 13,500 age-matched controls.

There was no greater risk of myocardial infarction among patients with retinal vein occlusion, according to Nancy M. Holekamp, MD, who presented the data here at the American Society of Retina Specialists annual meeting.

However, "after adjusting for confounders, retinal vein occlusion patients have approximately a twofold increased risk for cerebrovascular accident compared to non-retinal vein occlusion controls, with a relative risk of 1.72," Dr. Holekamp said.