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Researchers: Standard needed to measure corneal, conjunctival epithelial staining

Eye Contact Lens. 2008;34(6): 312-316.

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A universal standard protocol for assessing corneal staining in soft contact lens wearers should be established, study authors said after retrospectively examining the records of 338 hydrogel contact lens wearers.

The study assessed the presence of and correlation between corneal and conjunctival staining in healthy young adults who averaged 26 years of age and were successfully wearing soft contact lenses. Conjunctival staining was found in 32.5% of subjects, and corneal staining was found in 19.5%. However, only 4.4% of subjects had conjunctival staining greater than grade 1 using the Cornea and Contact Lens Research Unit scale, and only 2.7% of subjects had epithelial staining greater than grade 1. No subjects had staining greater than grade 2.

No statistically significant association could be demonstrated between staining and age, sex, refractive power, lens type worn, wearing modality and solution used.

Prevalence of staining in this study was lower than in previous studies, but the authors said "without some degree of protocol uniformity, it will remain difficult to compare the findings of different clinical studies."