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Repeat endothelial keratoplasty a viable alternative to PK

Cornea. 2011;30(11):1183-1186

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Repeat endothelial keratoplasty is a viable alternative to penetrating keratoplasty in patients with previous failed deep lamellar endothelial keratoplasty, according to a study.

The retrospective case series reviewed the clinical records of patients who underwent repeat endothelial keratoplasty after failed deep lamellar endothelial keratoplasty, or DLEK. Ten eyes of nine patients with a mean age of 71.2 years were included in the study. The mean time to repeat endothelial keratoplasty was 47 months, with a mean subsequent follow-up time of 21.7 months.

At final follow-up, corneal clarity and visual acuity had improved in all eyes. Mean preop logMAR best corrected visual acuity improved from 1.46 to 0.64 (P = .03).

"Although DLEK has been superseded by Descemet stripping techniques, patients are now presenting with failed DLEK requiring further surgical intervention, such as repeat EK or PK," the study authors said. "Repeat EK after late DLEK failure is an easily accomplished alternative to PK and results in improved visual acuity and corneal clarity."