Renal insufficiency may be linked to ROP development
The incidence of retinopathy of prematurity is high among infants born at less than 26 weeks gestation, according to a study. These infants are also more likely to develop ROP if renal insufficiency is present as a result of the premature birth age, the study authors note.
K. Allegaert, MD, and colleagues with the EpiBel Study Group in Belgium studied 303 infants believed to be between 22 and 26 weeks gestational age at birth. Of those infants, only 175 survived. The incidence of major retinopathy was 25.5% and the incidence of threshold retinopathy was 19.8%.
Threshold ROP without additional mobidity characteristics at discharge was documented in 14 infants. Renal insufficiency was determined to be a risk factor to develop threshold ROP (P < .0015). Days of respiratory support, the number of transfusions and renal insufficiency remained independent risk factors to develop threshold ROP.
The study is published in the February issue of British Journal of Ophthalmology.