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Regenerative factor-rich plasma effective treatment for moderate, severe ocular alkali burns
Eur J Ophthalmol. 2009; 9(6):909-915.
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Subconjunctival application of regenerative factor-rich plasma for patients with moderate chemical burns resulted in a significant reduction in corneal and conjunctival epithelization times, sick leave and healing time when compared with a control group.
In patients with severe chemical burns, a study found a significant reduction in time to corneal scarring in those treated with subconjunctival application of autologous regenerative factor-rich plasma. Results in that group were "at least as effective and [had] less side effects than the autohemotherapy."
"Subconjunctival infiltration with autologous [regenerative factor-rich plasma] can be considered an effective, straightforward and economical form of treatment for burns of the ocular surface," the authors said.
The study looked at 35 eyes of 35 patients who had ocular alkali burns, divided into groups based on severity of burns. Conventional topical medical treatment in a control group of moderate and severe burns was compared with autologous regenerative factor-rich plasma treatment in the moderate burn group and autohemotherapy to those receiving plasma in the severe burn group.
Patients were followed until healed.