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Psychophysical tests have different sensitivities to PCO, study finds

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Central posterior capsule opacification affects psychophysical test results with differing degrees of sensitivity, according to a British study. Of several types of tests evaluated, forward light scatter was the most sensitive and high-contrast visual acuity the least sensitive.

William R. Meacock and colleagues at St. Thomas’ Hospital in London studied 106 eyes that had undergone uncomplicated phaco. The percentage area of posterior capsular opacification within the central 3-mm zone of the posterior capsule was calculated using a digital retroillumination camera and special software.

The percentage of posterior capsule opacification required for a decline on the high-contrast Early Treatment Diabetic Retinopathy Study visual acuity chart was 78%; for low-contrast acuity and Pelli-Robson contrast sensitivity testing, the level was 46%; for CSV-1000 contrast sensitivity, 38% to 51%; and for forward light-scatter, less than 1%.

The study is published in the November issue of Investigative Ophthalmology & Visual Science.