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Prophylactic cefuroxime cuts postop endophthalmitis risk
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NEW ORLEANS — A postoperative cefuroxime injection effectively reduced the incidence of endophthalmitis after cataract surgery, according to a recent study.
"In this study, we aimed to perfect intracameral prophylaxis in our patient group," Gungor Sobaci, MD, said at the American Academy of Ophthalmology meeting here.
The study he presented included 3,221 patients who received an intracameral cefuroxime injection after undergoing phacoemulsification. The control group included 3,630 patients who underwent phacoemulsification without the injection, Dr. Sobaci said.
All patients received foldable hydrophilic intraocular lenses, he said. Postoperative endophthalmitis was identified in cases where inflammation required fluid samples, Dr. Sobaci said.
Results showed that four patients in the study group and 14 patients in the control group developed postoperative endophthalmitis, Dr. Sobaci said.
Dr. Sobaci pointed out that the study design was limited by its retrospective nature. However, the results still showed a significant reduction of endophthalmitis after receiving the intracameral cefuroxime injection, he said.