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Presentation of endophthalmitis after intravitreal steroids varies
Bacterial and noninfectious endophthalmitis after intravitreal triamcinolone injection can be distinguished by clinical signs and symptoms, a review of patient records suggests.
Mark L. Nelson, MD, and colleagues at Philadelphia’s Wills Eye Hospital analyzed the records of two patients with culture-proven bacterial endophthalmitis and six patients with presumed noninfectious endophthalmitis after intravitreal triamcinolone acetonide injection.
They determined that bacterial endophthalmitis after intravitreal injection of the steroid may present in an atypical and relatively delayed manner, with decreased vision but no pain or redness. Presumed noninfectious endophthalmitis, on the other hand, presented within 2 days after the injection, and may be accompanied by discomfort and hypopyon that may be the triamcinolone itself. In these eyes, hypopyon and symptoms resolved rapidly without treatment.
The study is published in Retina.