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Presence of iridocorneal angle pigment correlated with elevated IOP in study

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The presence of iridocorneal angle pigment is significantly correlated with elevated IOP in patients with pseudoexfoliation glaucoma, whereas the presence of pseudoexfoliation material in the anterior lens capsule is not, a study found.

Lesya Shuba, MD, PhD, of Dalhousie University in Nova Scotia, Canada, and colleagues graded photographs of iridocorneal pigment and pseudoexfoliation material in 98 patients with pseudoexfoliation glaucoma. The researchers then correlated their results with untreated IOP and functional and anatomical indices of glaucoma severity.

Dr. Shuba and colleagues found a positive statistically significant correlation between iridocorneal pigmentation and presenting IOP (P = .047) but not with glaucoma severity (P > .13). The grade of angle pigmentation was significantly higher in eyes with IOP greater than 21 mm Hg (P = .04), the authors said.

Pseudoexfoliation material in the anterior lens capsule was not correlated with IOP or glaucoma severity (P > .42), they noted.

The study is published in the January issue of the Journal of Glaucoma.