April 08, 2003
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Pre-PDR eyes likely to have impaired posterior pole, study says

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SAKURA, Japan — Retinal function in the posterior pole is markedly impaired in eyes with pre-proliferative diabetic retinopathy, according to a study.

Hiroyuki Onozu and Shuichi Yamamoto, both with Toho University Sakura Hospital here, compared multifocal electroretinograms from 61 eyes with pre-proliferative diabetic retinopathy (PDR) to 16 normal eyes.

All measurement variables were smaller in the eyes with pre-PDR than in the normal eyes, and the degree of reduction was greater for the oscillatory potentials of the electroretinogram. After panretinal photocoagulation, the amplitudes of the oscillatory potentials were significantly reduced in the peripheral regions; the changes in implicit times were not significant.

The study is published in the May issue of Documenta Ophthalmologica.