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Posterior vitreous detachment associated with dry AMD, vitreomacular adhesion with wet

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ATLANTA — Posterior vitreous detachment was highly associated with dry age-related macular degeneration while wet AMD was associated with vitreomacular adhesion, a surgeon said here.

"PVD [Posterior vitreous detachment] is highly associated with dry AMD and nearly half of eyes with wet AMD have vitreomacular adhesion," Susanne Binder, MD, said during Retina Subspecialty Day preceding the American Academy of Ophthalmology annual meeting. "3-D high resolution OCT provides useful information about the vitreoretinal relationship in this disease."

Excluding patients with end-stage AMD, 89% of eyes with dry AMD had complete posterior PVD, compared to 25% in wet AMD. Vitreomacular adhesion was seen in 50% of these patients with wet AMD, compared to 15% in dry AMD.

The prospective studies used flourescein angiography, OCT and photography to examine AMD patients 55 and older.