March 05, 2004
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Post-LASIK regression attributed to corneal protrusion, not thickening

Refractive regression after LASIK might be induced by corneal protrusion rather than central corneal thickening, according to a study.

Qing Pan and colleagues compared 15 eyes of nine patients with refractive regression post-LASIK with 15 eyes of 11 patients who had no refractive regression. Central corneal thickness (CCT) and anterior/posterior corneal curvature radiuses (CCR) were measured via Orbscan slit scanning before and 1 week, 1 month and 3 months after LASIK for the treatment of myopia.

Both groups had similar time courses of CCT but differed in time courses of corneal shifting movements. In the regression group, the postop posterior CCR were relatively stable. In the non-regression group, postop posterior CCR at week 1 had significantly steeper curvature than at month 3 postop. Anterior CCR in the regression group at week 1 had a significantly flatter curvature than at month 3; in contrast, no significant change of anterior CCR postop occurred with the non-regression group.

The study is published in the March/April issue of Ophthalmologica.