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Poor prognosis remains for patients with adenoid cystic carcinoma of the lacrimal gland

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Patients with adenoid cystic carcinoma of the lacrimal gland generally have a grave prognosis even after tumor removal, according to a long-term study.

Bita Esmaeli, MD, and colleagues at the M.D. Anderson Cancer Center in Houston retrospectively reviewed the charts of 20 patients diagnosed with adenoid cystic carcinoma of the lacrimal gland between 1952 and 2002. Disease-free survival rates were measured from the time of treatment completion, while overall survival rates were measured from the date of the initial diagnosis. Treatments included exenteration with bone removal and radiation therapy, exenteration with radiation therapy only, exenteration only, exenteration with bone removal only, local resection with radiation therapy and local resection alone.

At the time of the report, 65% of the patients had died because of the disease. Treatment type had no bearing on survival, the authors noted.

The study is published in Ophthalmic Plastic and Reconstructive Surgery.