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Pigment epithelial detachments follow similar clinical course
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MUNSTER, Germany — All pigment epithelial detachments follow a similar clinical course with respect to visual loss and enlargement or regression, despite different associations. This conclusion, drawn from a study of elderly patients here and in London, lends credence to a common pathogenetic background for the condition.
Researchers here performed fluorescein and indocyanine green angiography in 101 consecutive patients with clinical signs of serous pigment epithelial detachments (PED) and drusen. The patients were between 53 and 87 years of age; 63 were female.
Several different types of serous PED were identified: polypoidal choroidal vasculopathy-associated PED in 14 patients, vascular PED in 72 and avascular PED in 15. All patients had similar progressive visual loss initially, followed by regression. Avascular PEDs were smaller than vascular PEDs, which were in turn smaller than choroidal PEDs.
The study is published in Graefe's Archive for Clinical and Experimental Ophthalmology.