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Phacotrabeculectomy without MMC has similar success in PACG, POAG patients

J Glaucoma. 2011;20(1):57-62.

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The success of single-site phacotrabeculectomy without the use of mitomycin C was similar for both primary angle-closure glaucoma patients and primary open-angle glaucoma patients, according to a study.

Researchers evaluated the records of 71 eyes of 63 patients with primary angle-closure glaucoma (PACG) and 72 eyes of 57 primary patients with primary open-angle glaucoma (POAG). Mean follow-up times for the two groups were 38.7 months and 41.7 months, respectively.

For study purposes, surgical success was characterized by achieving an IOP of 21 mm Hg or less without the aid of anti-glaucoma medication or additional surgery, the study authors said.

In the PACG group, 72.1% of patients experienced complete success, compared with 56.1% of POAG patients. The difference, however, was not considered statistically significant.

Qualified success, which was defined as IOP less than 21 mm Hg with medications, was achieved by 87.4% of PACG patients and 92.8% of POAG patients, the study said.

The authors also noted that patients in the PACG group achieved a greater IOP reduction (P = .03) and required fewer postoperative anti-glaucoma medications to control IOP (P = .03).