December 03, 2009
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Pediatric donor tissue successfully used for DSEK in pseudophakic bullous keratopathy cases

Br J Ophthalmol. 2009;93(12):1625-1628.

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In a small study, the majority of pseudophakic bullous keratopathy cases had successful Descemet stripping endothelial keratoplasty with pediatric donor graft.

"With high postoperative endothelial cell counts, low graft dislocation rate and absence of high myopic shifts, pediatric donor tissue can be successfully used in DSEK," the study authors said.

The retrospective non-comparative interventional case series looked at seven eyes with pseudophakic bullous keratopathy that underwent DSEK with pediatric donor tissue that was unfolded in a "hitch suture" technique with air. Follow-up was 12 to 18 months.

The study found that six of the seven eyes underwent successful DSEK with pediatric donor graft. During dissection, one donor graft perforated. Graft dislocation did not occur in any eyes.

"At 12 months postoperatively, the cornea was clear in all eyes; the best spectacle-corrected visual acuity ranged from 20/67 to 20/32," the authors said.

Spherical equivalent refractive error averaged 1.9 D, corneal astigmatism averaged 2.2 D, corneal curvature averaged 45.2 D, and endothelial cell density averaged 2,247.7 cells/mm², they said.