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PDT can be effective in non-AMD CNV

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WAILEA, Hawaii — Younger patients, patients with relatively good vision and patients with predominantly classic choroidal neovascularization can be candidates for photodynamic therapy, one physician said.

“PDT probably works better than anti-VEGF drugs for [choroidal neovascularization in] non-age-related macular degeneration,” said Nancy M. Holekamp, MD, here at Retina 2006, held in conjunction with Hawaiian Eye 2006.

Dr. Holekamp described results of the VIP (Verteporfin in Photodynamic Therapy) Study Report No. 3. Change in visual acuity at 2 years was “in favor of the treated eyes,” she said.

An improvement of greater than one line was seen in 40% of treated eyes vs. 13% of untreated eyes, she said. In addition, there was improvement of more than three lines in 12% of eyes.

“The change in visual acuity at 2 years was in favor of the PDT-treated group. This group was more likely to have improved visual acuity through 2 years,” Dr. Holekamp said.