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PCO more extensive in hydrophilic than hydrophobic IOLs in study

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Posterior capsular opacification was significantly more extensive in eyes implanted with a hydrophilic hydrogel IOL than in eyes with a hydrophobic acrylic IOL, according to a Japanese study.

Ken Hayashi, MD, and colleague at the Hayashi Eye Hospital in Fukuoka studied 95 patients, each of whom had a hydrogel IOL implanted in one eye and an acrylic IOL implanted in the other. PCO was measured at 1, 6, 12, 18 and 24 months postoperatively using Scheimpflug photography. YAG capsulotomy rate and visual acuity were also measured.

The mean PCO value in the hydrogel group increased significantly (P < .0001) while the value in the hydrophilic group did not change. Throughout the follow-up period, the PCO value in the hydrogel group was significantly greater.

The rate of YAG capsulotomy in the hydrogel group was significantly greater than in the acrylic group (P < .0001). Mean VA in the hydrogel group decreased with time and became significantly worse than the mean VA in the acrylic group at 18 and 24 months postop.

The study is published in the February issue of British Journal of Ophthalmology.