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Patients with phakic lenses run small risk of developing CNV

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ALICANTE, Spain — Using phakic IOLs to correct high myopia may result in a small incidence of choroidal neovascularization, a study here found. A resultant effect is significantly decreased best corrected visual acuity, authors wrote.

José Ruiz-Morena, MD, and colleagues with the University Miguel Hernández found choroidal neovascularization (CNV) occurred in five eyes of 294 implanted with a phakic IOL for the correction of high myopia. Mean follow-up was 51 months, with a range of 6 to 120 months.

The interval between the phakic IOL implantation and onset of CNV ranged from 18 to 87 months. CNV was deemed subfoveal in four eyes and juxtafoveal in one eye. Mean best-corrected visual acuity (BCVA) after implantation but before CNV onset was 20/50 to 20/25. After CNV onset, BCVA decreased to 20/400 to 20/40. In two cases, the CNV was successfully treated with photodynamic therapy (PDT); in the other three, PDT was rejected.

The study was published in the February issue of Journal of Cataract & Refractive Surgery.