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Patients with DME have higher rates of perifoveolar posterior vitreous detachment

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Perifoveolar posterior vitreous detachment may play a role in the development of diabetic macular edema, a study using optical coherence tomography suggests.

David Gaucher, MD, and colleagues at the Lariboisière Hospital in Paris studied 49 eyes of 35 patients with diabetic macular edema and 35 patients with diabetes who did not have diabetic macular edema. Optical coherence tomography was used to obtain cross-sectional images of the vitreoretinal interface of the macular region. Posterior vitreous detachment (PVD) in the eyes was rated on a scale from 0 to 3: Stage 0 was absence of PVD; stage 1 was perifoveolar PVD with foveolar attachment; stage 2 was incomplete PVD with residual attachment to the optic nerve; and stage 3 was complete PVD.

Of the eyes with macular edema, 19 were stage 0 (38.8%), and 26 were stage 1 (53%). In the eyes without macular edema, 34 were stage 0 (69.4%) and 11 were stage 1 (22.4%). In both groups, one eye was stage 2 and three eyes were stage 3.

The authors said the prevalence of perifoveolar PVD with foveolar attachment was significantly higher in the eyes with DME.

The study is published in the May issue of American Journal of Ophthalmology.