April 30, 2010
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Optic neurotomy, triamcinolone appear to be most effective for treatment of CRVO

Ophthalmic Surg Lasers Imaging. 2010;41(2):157-165.

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Radial optic neurotomy and intraocular triamcinolone injection proved to be the most effective treatment protocol for patients with central retinal vein occlusion in a study comparing five different treatment approaches.

Best corrected visual acuity improved by a mean –0.50 logMAR 6 months after radial optic neurotomy and an intraocular injection of triamcinolone. Patients who received intravitreal triamcinolone improved by a mean –0.31 logMAR at 6 months; patients who underwent internal limiting membrane peeling, radial optic neurotomy and intraocular triamcinolone injection improved a mean –0.12 logMAR at 6 months; patients who underwent radial optic neurotomy alone improved a mean –0.10 logMAR at 6 months; and patients who underwent no treatment improved a mean –0.09 logMAR at 6 months.

"According to this study, we may recommend radial optic neurotomy with adjunctive intraocular triamcinolone in patients with CRVO and low vision to gain better BCVA at least for 6 months," the study authors wrote.

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