July 20, 2011
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Optic nerve damage patterns differ in chronic angle-closure, primary open-angle glaucoma

Am J Ophthalmol. 2011;152(1):74-80.

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Chronic angle-closure glaucoma eyes had less paracentrally located visual field loss than did eyes with primary open-angle glaucoma, according to a study.

In a retrospective, cross-sectional study performed on 64 eyes of 64 patients, 32 patients had chronic angle-closure glaucoma and 32 had primary open-angle glaucoma. Heidelberg Retina Tomograph (HRT, Heidelberg Engineering) images and stereoscopic disc photographs were obtained within 1 year of visual field test showing reproducible glaucomatous field loss. Focal rim loss, location and amount of field loss were measured in all patients.

Results showed no focal rim loss difference between the two groups. Eyes with chronic angle-closure glaucoma had smaller cup-to-disc-area ratios, shallower cups and larger rim-to-disc ratios. HRT results showed a prevalence of localized rim loss in the inferotemporal sector of the disc.

“We hypothesized that patterns of glaucomatous damage in [chronic angle-closure glaucoma] are different from those in eyes with [primary open-angle glaucoma],” the study authors said, adding that such findings “may have significant implications with regard to early detection of the disease and its progression in eyes with chronic angle-closure glaucoma.”