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Optic edge key factor in PCO prevention, study finds

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The sharpness of the optic edge may play a critical role in the prevention of posterior capsule opacification, even more so than haptic angulation, according to an animal study.

Masahiko Ayaki and colleagues compared lens epithelial migration of acrylic lenses with three different finishes (no finish, polishing and tumbling, and polishing) and two types of haptic angulation (10º and 15º). These were compared with the AcrySof (Alcon), the Sensar (AMO) and the CeeOn (Pfizer) IOLs implanted in rabbit eyes.

Scanning electron-microscopic exam showed the optic edge sharpness decreasing according to the finishes in the experimental IOLs. Migration score was highest in the Sensar and lowest in IOLs with sharp edges and large haptic angulation.

The study is published in the August issue of Ophthalmic Research.