October 07, 2010
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One-piece acrylic IOL shows higher pupillary capture rate than three-piece design

J Cataract Refract Surg. 2010;36(10):1645-1649.

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A one-piece IOL was more strongly associated with pupillary IOL capture of the IOL optic than a three-piece IOL during combined cataract surgery and pars plana vitrectomy, a study found.

In addition, vitreous substitutes were associated with elevated rates of posterior synechiae formation.

"Given that both IOL types can be injected intraocularly using the same cartridge system, there is little downside to using three-piece IOLs when performing combined cataract and vitrectomy surgery," the study authors said.

The retrospective comparative case series included 145 patients who underwent combined cataract surgery and vitrectomy; 89 patients received one-piece acrylic IOLs and 56 patients received a three-piece acrylic IOL.

Results showed that seven patients who received one-piece IOLs and no patients who had three-piece IOLs experienced IOL capture; the between-group difference was statistically significant (P = .043).

Data showed that both IOL types had similar rates of posterior synechiae formation. However, 96.4% of patients with posterior synechiae had undergone vitreous replacement with silicone oil, sulfur hexafluoride or perfluoropropane, the authors said.

"An expanding gas tamponade has been independently shown to be a risk factor for the formation of synechiae and pupillary capture after combined surgery," they said.