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Olopatadine more effective than ketorolac for ocular itching in small study
Olopatadine was found to be more effective at reducing ocular itching than ketorolac tromethamine, a small Turkish study found. Both olopatadine and ketorolac alleviated clinical signs and symptoms of seasonal allergic conjunctivitis in comparison to placebo in the single-center study.
Volkan Yaylali, MD, and colleagues at the Pamukkale University School of Medicine studied 40 patients with signs and symptoms of seasonal allergic conjunctivitis. One eye of 20 patients was treated with olopatadine and the other with placebo; in the second group of 20, one eye was treated with ketorolac and the other with placebo. Follow-up was at 30 minutes, 2, 7 and 15 days.
The itching score was significantly lower in the olopatadine group from the second day through the end of the study. Both groups fared similarly in reduction of signs and symptoms of allergic conjunctivitis when compared to placebo.
The study is published in the August issue of Acta Ophthalmologica Scandinavica.