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Ocular response analyzer detects minor corneal changes after cross-linking
BARCELONA — Wavefront parameters can expand the potential analysis of biomechanical changes of the cornea before and after corneal cross-linking, according to a speaker here.
 Maria A. Woodward |
In a presentation at the European Society of Cataract and Refractive Surgeons meeting, Maria A. Woodward, MD, said collagen cross-linking changes the biomechanical properties of the cornea, but no changes were detected using Ocular Response Analyzer (ORA, Reichert) technology. She used ORA in her study of 23 eyes in 18 patients with corneal ectasia before and after cross-linking.
Sequential scans were taken the day of cross-linking and at least 3 months later. There were no statistically significant differences in the majority of waveform parameters analyzed, including corneal hysteresis, corneal resistance factor and the shape of the ORA curves. However, there were significant changes in the pressure-related ORA parameters after cross-linking, she said.
Dr. Woodward said the current tools for corneal analysis are either not sensitive enough to detect the biomechanical changes or do not address the fundamental changes produced by collagen cross-linking. ORA technology may have potential use in ectasia management and refractive surgery screening.