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Ocular pulse amplitude may help detect normal tension glaucoma

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MAINZ, Germany — Measuring ocular pulse amplitude could be helpful in detecting normal tension glaucoma, according to a study.

Researchers here at Johannes Gutenberg University used the SmartLens tonometer (Ophthalmic Development Co.) to measure and record simultaneously both intraocular pressure and ocular pulse amplitude in 80 subjects. The patients were divided equally into four groups of people with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), ocular hypertension and controls. The control group had no ocular pathology aside from cataract.

The ocular pulse amplitude of people with POAG was not statistically different from either the control group or the ocular hypertension group. In people with NTG, however, the ocular pulse amplitude was statistically significantly lower (P < .01) compared with the other groups. People with ocular hypertension showed slightly higher amplitude rates than healthy volunteers or those with POAG.

The study is published in the September issue of British Journal of Ophthalmology.