February 28, 2011
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OctoPlus to develop controlled-release ophthalmic formulation

LEIDEN, Netherlands — OctoPlus has entered into a contract with ESBATech to develop a controlled-release formulation of a proprietary biological compound for ophthalmic indications, the company announced in a press release.

The contract includes process development, scale-up and manufacturing for pre-clinical studies of Locteron, which is part of a portfolio of projects focused on proprietary technologies, the release said.

The controlled-release formulation combines a proprietary eye care ingredient of ESBATech with PolyActive, a drug delivery technology from OctoPlus.

"Ophthalmology is a rapidly growing therapeutic area, and there is a strong and obvious need to reduce the injection frequency of drugs that are administered into the eye," Jan H. Egberts, MD, CEO of OctoPlus, said in the release.

Although the financial details were not disclosed, the project will make a material contribution to OctoPlus' revenue for 2011, the release said.