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NSAIDs show little effect on development of CME
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PHILADELPHIA — Use of prophylactic nonsteroidal anti-inflammatory drugs did not significantly reduce rates of cystoid macular edema in patients undergoing cataract surgery when compared with non-prophylactically treated eyes, according to a study presented here.
"In our subset of low-risk patients, prophylactic use of NSAIDs at the time of cataract surgery was not associated with a lower rate of CME," Fatima K. Ahmad, MD, said at the Wills Eye Institute Alumni Conference.
In the retrospective review of 925 eyes of 700 patients who underwent cataract surgery at the Wills Eye Cataract and Primary Eye Care Service between 2007 and 2010, 234 eyes did not receive perioperative NSAIDs and 648 eyes did.
Pseudophakic cystoid macular edema developed in 29 patients at a rate of 3.2% in the group that did not receive NSAIDs and a rate of 3.4% in the group that received NSAIDs.
"We will continue to gather data," Dr. Ahmad said. "This will help us determine whether prophylactic NSAID use has been associated with an anti-CME rate as well as visual acuity outcomes."
- Disclosure: Dr. Ahmad has no relevant financial disclosures.