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Not all acute posterior multifocal placoid pigment epitheliopathy patients have full visual recovery

Retina. Published online ahead of print May 27, 2009. PMID: 19491729.

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After treatment, patients with acute posterior multifocal placoid pigment epitheliopathy may still be symptomatic at last follow-up, with mixed visual acuity results, a study found.

"Although acute posterior multifocal placoid pigment epitheliopathy shows a relatively benign prognosis, especially when compared with some of the other white dot syndromes, there are patients who experience incomplete visual recovery," the study authors said.

They examined cases of acute posterior multifocal placoid pigment epitheliopathy, both treated at the Massachusetts Eye and Ear Infirmary between 1990 and 2002 and from literature.

At presentation, they found that 226 eyes (76.6%) had visual acuity of 20/25 or worse, while 172 eyes (58.3%) saw 20/40 or worse. By the last follow-up, 125 eyes (42.3%) had visual acuity at 20/25 or less; 70 eyes (23.7%) saw 20/40 or less. At that time, 87 eyes (71.9%) were still symptomatic.

Topical or systemic therapy was administered to 54.4% of cases.