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Normal tension glaucoma progresses in central visual field faster than exfoliative high-tension glaucoma
Invest Ophthalmol Vis Sci. 2009;doi:10.1167/iovs.09-3806.
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Normal tension glaucoma cases showed higher rates of progression in the central visual field than exfoliative high-tension glaucoma cases, according to a study.
Researchers found that paracentral visual field progression was significantly more common in a normal tension glaucoma group, at a rate of 75%, than an exfoliative high-tension glaucoma group, at a rate of 57.3%.
"[Exfoliative high-tension glaucoma] and [normal tension glaucoma] eyes progress at a similar global rate after adjustment for differences in IOP, [central corneal thickness] and age. However, [normal tension glaucoma] eyes progressed more often in the central [visual field], independent of other factors," the authors said.
The chart review examined 139 normal tension glaucoma eyes with IOP lower than 21 mm Hg and 154 exfoliative high-tension glaucoma eyes with untreated IOP of 21 mm Hg or more. Subjects were in the New York Glaucoma Progression Study.
Patients had at least five SITA-Standard 24-2 visual fields. For global and localized rates of change, automated pointwise linear regression analysis was used.
The study found that exfoliative high-tension glaucoma cases progressed globally nearly twice as fast as normal tension glaucoma cases; however, when adjusted for age, mean IOP and central corneal thickness, the difference was not significant.