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Non-mydriatic fundus photography may be accurate in detecting retinal disease
Ophthalmic Surg Lasers Imaging. 2011;42(2):102-106.
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Single-field non-mydriatic fundus photography may be accurate and sensitive for screening retinal diseases, a study found.
The retrospective review included 1,175 patients at the Cleveland Clinic who had both eyes photographed. All images incorporated a 45° field of the posterior pole, showing the optic nerve and macular area.
Photographs for the two eyes were adequate for interpretation in 95.1% of patients. Poor quality images were not centered, failed to capture the macula or optic nerve, or were too dark.
Eighty-five percent of patients showed normal results, and of the remaining patients with abnormalities, the most common findings were macular degeneration, optic nerve cupping, hypertensive retinopathy and choroidal nevi.
Fifty-five of 166 patients with abnormalities had known follow-up, and of these, seven showed normal eye examination results. Five had small drusen, which could be classified as unremarkable by some clinicians, and two had retinal hemorrhages that may have resolved before follow-up.
The study authors said that not being able to determine the false-positive rate was a major limitation and that image quality may improve with trained personnel, dimmer lighting or more time for pupil dilation.