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No significant relationship between diabetes mellitus, exfoliation syndrome in US Veterans Affairs population
J Glaucoma. 2010; doi: 10.1097/IJG.0b013e3181e3d483.
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Contrary to previous research suggesting an inverse relationship between diabetes mellitus and exfoliation syndrome, more cases of diabetes mellitus were found in patients without exfoliation syndrome than in those with the syndrome, a population study found.
"In this predominately white male population, we did not observe a statistically significant relationship between diabetes mellitus and [exfoliation syndrome]," the study authors wrote. "In addition, HbA1c levels did not vary among diabetic patient based on exfoliation status."
The retrospective, case-control study examined 328 exfoliation patients and 328 controls from the Veterans Affairs Boston Healthcare System eye clinics. Patients were matched for age in the study. Diabetes status, gender, race, body mass index and glaucoma status were recorded. Method of diabetes control and five of the most recent HbA1c levels were collected from diabetes mellitus patients.
According to study results, 96 (29.2%) exfoliation cases had diabetes mellitus, while 114 (34.8%) controls had it.
Adjusted mean HbA1c levels were similar among diabetic patients with (6.85%) and without (7.05%) exfoliation syndrome.
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