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No evidence of iris abnormalities in latanoprost-treated eyes in EM study
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MAINZ, Germany — Eyes treated with latanoprost and fellow untreated eyes showed no differences in the ultrastructure of the iris after 6 months of treatment, according to an electron microscopic study.
Norbert Pfeiffer, MD, and others here at Johannes Gutenberg-Universität recruited 17 patients with bilateral primary open-angle glaucoma undergoing trabeculectomy into a study. The iridectomy taken during surgery on each patient’s first eye served as a control. The second eye of each patient was treated topically with latanoprost for 6 months before trabeculectomy. A total of 31 specimens were evaluated for evidence of stromal inflammation, vascular alterations and stromal and posterior epithelial degeneration. The treated and untreated eyes all conformed to published standards for normal iris, the authors said.
The study is published in the January issue of Archives of Ophthalmology.