New technique shows promise for detecting macular degeneration
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SALT LAKE CITY Raman spectroscopy may be effective as a screening tool for macular degeneration, according to research from the University of Utah.
Researchers here used Raman spectroscopy to image the spatial distribution of macular carotenoid pigment in eye bank eyes. Using resonant excitation of the pigment molecules with narrow-bandwidth blue light from a mercury arc lamp, researchers recorded Raman images originating from the carbon-carbon double bond stretch vibrations of the molecules.
The study authors said their research demonstrates the potential for using the method in large-scale population studies to provide insight in individual variations in the spatial profiles of macular carotenoid pigment distributions as well as the total amounts of macular carotenoid pigment.
The study will be published in the June issue of Journal of the Optic Society of America A.