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New risk factors for retinal disorder identified

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Antibiotics, antihistamines, alcohol use, tobacco use, untreated hypertension and multi-system autoimmune diseases are potential risk factors for central serous chorioretinopathy, according to a study in the February issue of Ophthalmology.

In the case-control study, the records of 312 patients with central serous chorioretinopathy (CSCR) and 312 patients with other ophthalmic conditions were examined. The study showed the strongest association of CSCR, a disorder in which the retinal cells detach and atrophy causing visual impairment and loss, was with systemic corticosteroid use and pregnancy.

“In addition, this study shows a wide variety of new systemic factors are associated with CSCR. These are alcohol, antibiotic, antihistamine and tobacco use and untreated hypertension and allergic respiratory disease,” said Sean Koh, MD, a vitreoretinal fellow in the Retina Service of the Massachusetts Eye and Ear Infirmary, Harvard Medical School, and a co-author of the study.