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Nerve fiber indicator best 'discriminating' measure with scanning laser polarimetry device

J Glaucoma. 2009;18(6):448-452.

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A study that examined retinal nerve fiber layer across three scan diameters using a scanning laser polarimetry device found that medium and large circles appeared to provide good glaucoma evaluation, while nerve fiber indicator provided the overall discriminating measurement.

"Medium and large circles can also be used for [retinal nerve fiber layer] evaluation in glaucoma. [Nerve fiber indicator] is the best discriminating measure across all scan diameters," the study authors said.

The study looked at results of the GDx VCC (Laser Diagnostic Technologies) device, used to determine retinal nerve fiber layer parameters in 100 subjects without glaucoma, 50 primary-open angle glaucoma suspects and 50 early primary-open angle glaucoma patients. Three different scan diameters of conventional small, medium and large circle were studied, the authors said.

They found that between normal and early primary-open angle glaucoma eyes, retinal nerve fiber layer parameters at all circles had a significant difference (P < .001).