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Myopic LASIK with 'aberration neutral' ablation profiles had minimal induced aberrations

J Refract Surg. 2009;25(11):991-999.

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Eighty-seven percent of myopic cases that underwent LASIK with aspheric "aberration neutral" ablations were within ±0.5 D of attempted correction at 3 months after the procedure, a study found.

"Our results show that non-customized 'aberration neutral' ablation profiles derived from wavefront analysis are able to minimize the amount of induced aberrations of both the cornea and the eye," the study authors said.

The study evaluated results of LASIK performed with a pendular microkeratome with a 130-µm cutting head and the ESIRIS excimer laser (Schwind) in 231 eyes of 120 patients. The cases had a mean spherical equivalent refraction of –4.12 D.

Preop and postop outcome measurements including autorefractor measurements, manifest refraction, best corrected visual acuity, uncorrected visual acuity, topography, corneal and ocular wavefront analysis, and complications were analyzed.

The researchers found that UCVA was 20/16 or better in 164 eyes (71%), 20/20 or better in 213 eyes (92%) and 20/32 in all eyes.

"Average root-mean-square higher-order aberrations increased 0.05 µm after treatment, mean spherical aberration increased 0.08 µm after treatment, and mean coma increased 0.04 µm after treatment (all for 6-mm analysis diameter)," they said.