June 02, 2010
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Myopia does not appear to be related to progression rate in normal-tension glaucoma

Am J Ophthalmol. 2010;149(5):831-838.

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No statistically significant difference was found for glaucoma progression rates between non-myopic patients and myopic patients, all of whom had normal-tension glaucoma, when multiple factors were compared and age and IOP after treatment were controlled, a study found

"Although a high incidence of open-angle glaucoma among myopic patients has been reported previously, myopia did not influence the progression rate of [normal-tension glaucoma] after treatment," the authors said.

The retrospective, observational case series examined 143 eyes of 143 normal-tension glaucoma patients. All patients received treatment between 1994 and 2006, with standard automated perimetry at follow-up. Patients were grouped by one of four classifications: mild myopia, moderate myopia, severe myopia or non-myopia.

The study compared mean deviation alteration, corrected pattern standard deviation and specific thresholds in the non-myopia group with the myopia groups. Age and IOP following treatment were controlled.

The study found that for mean deviation, corrected pattern standard deviation, mean thresholds of 10 zones corresponding with the glaucoma hemifield test and thresholds of 52-point changes against refraction, there was no statistically significant difference between the non-myopia and myopia groups.

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