This article is more than 5 years old. Information may no longer be current.
Modified ILM staining technique may help avoid adverse effects
A modified approach to staining of the internal limiting membrane can limit the amount and concentration of indocyanine green and help avoid adverse side effects, according to a recent paper.
Joerg C. Schmidt and colleagues at Philipps University in Marburg, Germany, describe a new technique to stain and peel the internal limiting membrane. After a core vitrectomy, 0.05 mL of indocyanine green (ICG) in a concentration of 5 mg/mL is injected under water around the macular region. The syringe tip is positioned about 5 mm from the macular tissue so that an area 3 mm in diameter around the fovea is stained by the ICG. Additional ICG is removed via aspiration. The ILM is then peeled with forceps.
No residual ICG in the vitreous cavity nor any clinical signs of phototoxicity were detected in any patient undergoing the modified technique, according to the authors.
The study is published in Ophthalmologica.